Why toxicologists resisted and radiation geneticists supported EPA’S adoption of LNT for cancer risk assessment

by Mark Miller | Jul 8, 2019 | LNT Hypothesis

https://www.sciencedirect.com/science/article/pii/S0009279719308634?via%3Dihub Abstract The linear non-threshold (LNT) dose response model for cancer risk assessment has been a controversial concept since its initial proposal during the 1930s. It was long advocated by...

Muller’s Nobel Prize data: Getting the dose wrong and its significance

by Mark Miller | Jul 8, 2019 | LNT Hypothesis

https://www.sciencedirect.com/science/article/pii/S0013935119303251?via%3Dihub This paper evaluates the significant historical paper of Muller and Mott-Smith (1930), which successfully disputed the proposal of Olson and Lewis (1928) that background ionizing radiation...

Assessing the Scientific Basis of the Linear No Threshold (LNT) Model with Threshold Models for Cancer Risk Assessment of Radiation and Chemicals

by Mark Miller | Jun 28, 2019 | Featured Articles, LNT Hypothesis

https://www.sciencedirect.com/journal/chemico-biological-interactions/vol/301/suppl/C If LNT were a biologically valid dose-response model, the appearance and evolution of life on Earth would not have been possible. This link contains a wide spectrum of papers...

Molecular Bioligy, Epidemiology and the Demise of the LNT Hypotesis

by Mark Miller | Jun 24, 2019 | LNT Hypothesis

dc-low-dose-Pollycove-Feinendegen-CR-Acad-Paris-99 Metabolic DNA damage/Radiation DNA damage = ~ 107 .  Low-Dose Radiation adds NOTHING to background cancer rates…says his paper published 20 years ago!  The message hasn’t changed. The effect of 1 mGy/year...

Interests, Bias, and Consensus in Science and Regulation

by Mark Miller | Jun 11, 2019 | Fear, Uncertainty and Doubt, Featured Articles, LNT Hypothesis

https://journals.sagepub.com/doi/full/10.1177/1559325819853669 Abstract Scientists are human. As such, they are prone to bias based on political and economic interests. While conflicts of interest are usually associated with private funding, research funded by public...

Linear No-threshold (LNT) vs. Hormesis Paradigms, Assumptions, and Mathematical Conventions that Bias the Conclusions in Favor of LNT and Against hormesis

by Mark Miller | May 22, 2019 | Hormesis, LNT Hypothesis

https://journals.lww.com/health-physics/Fulltext/2019/06000/Linear_No_threshold__LNT__vs__Hormesis__Paradigms,.7.aspx The linear no-threshold assumption misunderstands the complex multiphasic biological response to ionizing radiation, focusing solely on the initial...